InVivo Therapeutics has a well-established Compliance Program that reflects a strong commitment to compliance with the laws and regulations that govern medical device and pharmaceutical development, marketing, and commercialization activities in the United States. InVivo Therapeutics’ Compliance Program adheres to the requirements of the U.S. Food and Drug Administration’s “Medical Device Quality Systems Manual,” and is consistent with, where applicable, the recommendations set forth in “Compliance Program Guidance for Pharmaceutical Manufacturers,” published by the Office of Inspector General, U.S. Department of Health and Human Services (the “HHS-OIG Guidance”). In addition, InVivo is committed to promoting and enforcing the provisions of the “Code of Ethics on Interactions with Health Care Professionals” as adopted by the Advanced Medical Device Technology Association (AdvaMed). The goal of our Compliance Program has always been to maintain a culture that promotes the prevention, detection, and resolution of potential violations of law or Company policy and appropriate and proactive identification and management of potential hazards in the development, research, and use of medical devices and their component or adjunctive therapies in human populations.